About Vatican Museum, to avoid queues, book your tickets at Vatican official site. Time your visit to reduce waiting. Wednesday mornings are good, afternoon is better than the morning, choosing lunch time is a smart idea. But attenzione! (Look out!). Manage your booking 2-3 weeks before your landing in Rome. Or you should see the Cappella Sistina only on the postcards!
Near Vatican city there is a very cool neighborhood with trendy restaurants and bars. I'm talking